AccuGenomics has developed Internal Standards (IS) for Standardized Nucleic Acid Quantification for Sequencing (SNAQ-SEQ) that provide a direct and precise quantification of SARS-CoV-2 sequence present in each sample. The IS acts as a positive control, comprised of a known set and quantity of RNA molecules that biochemically mimic the behavior of the SARS-CoV-2 genome present in each sample.
The IS, when added, indicates if every sample achieves sufficient analytic sensitivity and specificity. Comparing the expected amount of IS product to the actual measured IS response allows for the genetic variability in the sample to be accurately quantifiable. AccuGenomics IS diagnostic testing standardizes the amount of information required for a sample to yield a valid result and allows for comparison across assays.
Created a shelf stable SNAQ SARS-CoV-2 Internal Standard material
Demonstrated Standardized Nucleic Acid Quantification (SNAQ) analysis benefits in an interlaboratory study, specifically analysis of viral load, sensitivity, and specificity
Help improve the nation's response to detecting new SARS-CoV-2 variants by ensuring quality surveillance data, leading to better COVID-19 diagnosis and treatment monitoring, and supporting more accurate and reliable development testing of future viral outbreaks
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