Chimeric antigen receptors (CARs) T-cell therapy has become an important approach for cancer treatment.
Develop a novel perfusion-based, beads-free, bioreactor system as a new platform for CAR t-cell manufacturing.
Developed an automatable, scalable, and closed bioreactor system and process for T-cell activation and expansion.
The development of this novel perfusion-based system would facilitate scaling the manufacturing of CAR T cells for different users.
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Southwest Research Institute
Genentech, Inc.
Merck Sharp & Dohme LLC
Xcellerate Biotech Inc.