Discover Negotiate Play (DNP) Development

Standard software allowing true plug and play of unit op components, reducing automation changes from months to days.
Categories
Proteins/ Antibodies
Project status
99% Completed

Industry Need

Automation changes take weeks to months, often on critical path for tech transfer.

Solution

Standard and software allowing true plug and play of unit op components.

Outputs/Deliverables

  • Interchangeability Demonstrations – SMART O2 sensors from different vendors used to connect to same HMI using the DNP / MTP automation platform while in-process (Complete December 7, 2021). Videos/recordings available upon request.
    • Demonstration 1: March 2021. MTP Connectivity using a smart pump
    • Demonstration 2: June 2021. Interchangeability with 1 smart sensor
    • Demonstration 3: July 2021. Interchangeability with 2 smart sensors
    • Beta Demonstration: December 2021. Demonstrate MTP connectivity and interchangeability between 2 smart sensors
  • Reconfigurability Demonstrations – added new processing capability (glucose control) during pre-process equipment setup without re-programming the HMI and process orchestration layer (Complete July 11, 2023). Videos/recordings available upon request.
    • Demonstration 1: June 2022. POL augmented with 1 smart actuator and 1 smart sensor.
    • Demonstration 2: November 2022. Extend existing MTP service to smart actuator.
    • Demonstration 3: July 2023. Adding new MTP service.
  • DNP Workshop. March 27th, 2024 in France.

Impacts

Reduce reconfiguration downtime from months to days (assume 4 wks savings).

Publications

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Project Lead

NIIMBL

NIIMBL

Participating Organizations

3M Company

3M Company

Amgen Inc.

Amgen Inc.

Bristol-Myers Squibb

Bristol-Myers Squibb

CSL Behring, LLC

CSL Behring, LLC

Cytiva

Cytiva

Eli Lilly and Company

Eli Lilly and Company

GlaxoSmithKline, LLC

GlaxoSmithKline, LLC

Janssen Research & Development, LLC

Janssen Research & Development, LLC

Merck Sharp & Dohme LLC

Merck Sharp & Dohme LLC

MilliporeSigma/EMD Serono

MilliporeSigma/EMD Serono

Pfizer, Inc.

Pfizer, Inc.

Sanofi

Sanofi

Sartorius Stedim

Sartorius Stedim