Rapid CHO Transcriptome Analysis for Adventitious Agent Detection
The goal of this project is to apply existing genomic analysis technologies to identify changes in miRNA expression in CHO that could be used to assay infection by adventitious agents (AA).
Categories
Assays
Project status
100% Completed
Industry Need
Current methods to reveal information on the health and productivity of cells used in the biomanufacturing processes include laborious processes steps and take several days to for analysis.
Solution
Apply existing genomic analysis technologies to identify changes in miRNA and/or mRNA expression in CHO that could be used to assay infection by adventitious agents.
Outputs/Deliverables
Discovered a set of miRNA biomarkers whose expression levels correlate with adventitious viral infection.
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