Process analytical technology aims to improve biomanufacturing by providing real-time information about the product, enabling real-time release. This team will use of spectroscopy techniques for continuous in-process monitoring of virus particles and establish the basis for a standardized detection method. Doing so will establish a standard method that follows FDA guidance for future manufacturing of vaccines and address the need for uniform and controlled platform approaches.
Successful completion of the project will lead to a spectro-acoustic process analytical technology that enables real-time quantification of virus particles necessary for continuous manufacturing of future vaccines towards coronaviruses.
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Purdue University
