A Multivariate In-Line Optochemical Sensor Platform for Continuous Monitoring of Cross-Category Process Parameters and Product Attributes in Bioreactors
This project develops a multi-attribute inline optochemical sensor platform for continuous monitoring of bioreactors at all scales. This multiplexed fiber-optic sensor platform will monitor, glucose, DO and DCO.
Categories
Process control
Project status
100% Completed
Solution
Performance Period: 2/1/2020 to 7/31/2021
This project develops a multi-attribute inline optochemical sensor platform for continuous monitoring of bioreactors at all scales. This multiplexed fiber-optic sensor platform will monitor, for the first time, cross-category variables, such as metabolites (e.g., glucose), dissolved O2 (DO) or dissolved CO2 (DCO). This technology will shorten conventional analytical tests for bioreactors from multiple days to real-time, which is a critical step toward ultimate closed feedback control loops that enable continuous and adaptable manufacturing.
Updates, Related Publications, and Deliverables
Login to the NIIMBL member portal for access to project updates, related publications, and deliverables.