Next Gen High Level Design of Facility Layout

Develop a Generation 2 solution in the form of a stand-alone facility layout, equipment list, project delivery methodology, high level cost estimate and implementation schedule.
Categories
Drug substance
Equipment and Supplies

Industry Need

Clarity on which technology and regulatory projects will deliver the vision for the future.

Approach

Conduct more detailed design and engineering to show value of NIIMBL projects.

Impacts

Detailed business case for integrated continuous bioprocessing (ICB) with capital cost estimates.

Line of sight from corporate manufacturing goals to NIIMBL projects.

Outputs/Deliverables

  • 1st Gen Facility Design (Complete, presented at BPI West 2024)
  • Equipment URS – (Complete, available on NIIMBL website)
  • 2nd Gen Facility Design – (Complete, presented at ICB 2024)

Presentations

Erickson, J., Presenter, Factory of the Future ICB Conference, ECI Integrated Continuous Manufacturing, Leesburg, VA, October 23, 2024

Erickson, J., Szuszkiewicz, R., Presenters, Bioprocess International West, Bioprocessing Facility Conceptual Design and Economics, San Diego, CA, March 13, 2024

Erickson, J., Workshop Chair, Factory of the Future and Enabling Technologies Workshop, NIIMBL National Meeting, Washington, DC, June 25, 2024

Szuszkiewicz, R., Presenter, NIIMBL Next Generation Manufacturing Facility, NIIMBL National Meeting, Washington, D.C., June 25, 2025.

Additional Project Information (Members Only)

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Project Lead

NIIMBL

NIIMBL

Participating Organizations

Amgen Inc.

Amgen Inc.

AstraZeneca

AstraZeneca

Bristol-Myers Squibb

Bristol-Myers Squibb

CSL Behring, LLC

CSL Behring, LLC

Cytiva

Cytiva

EMD Millipore Corporation

EMD Millipore Corporation

Eli Lilly and Company

Eli Lilly and Company

Genentech, Inc.

Genentech, Inc.

GlaxoSmithKline, LLC

GlaxoSmithKline, LLC

IPS-Integrated Project Services, LLC

IPS-Integrated Project Services, LLC

Janssen Research & Development, LLC

Janssen Research & Development, LLC

Merck Sharp & Dohme LLC

Merck Sharp & Dohme LLC

Pfizer, Inc.

Pfizer, Inc.

Sanofi

Sanofi

Sartorius Stedim

Sartorius Stedim

Takeda Pharmaceuticals

Takeda Pharmaceuticals