Discover Negotiate Pair (DNP) Development

Standard software allowing true plug and play of unit op components, reducing automation changes from months to days.
Categories
Proteins/ Antibodies

Industry Need

Automation changes take weeks to months, often on critical path for tech transfer.

Solution

Standard and software allowing true plug and play of unit op components.

Outputs/Deliverables

  • Interchangeability Demonstrations – SMART O2 sensors from different vendors used to connect to same HMI using the DNP / MTP automation platform while in-process (Complete December 7, 2021). Videos/recordings available upon request.
    • Demonstration 1: March 2021. MTP Connectivity using a smart pump
    • Demonstration 2: June 2021. Interchangeability with 1 smart sensor
    • Demonstration 3: July 2021. Interchangeability with 2 smart sensors
    • Beta Demonstration: December 2021. Demonstrate MTP connectivity and interchangeability between 2 smart sensors
  • Reconfigurability Demonstrations – added new processing capability (glucose control) during pre-process equipment setup without re-programming the HMI and process orchestration layer (Complete July 11, 2023). Videos/recordings available upon request.
    • Demonstration 1: June 2022. POL augmented with 1 smart actuator and 1 smart sensor.
    • Demonstration 2: November 2022. Extend existing MTP service to smart actuator.
    • Demonstration 3: July 2023. Adding new MTP service.
  • DNP Workshop. March 27th, 2024 in France.

Impacts

Reduce reconfiguration downtime from months to days (assume 4 wks savings).

Publications

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Project Lead

NIIMBL

NIIMBL

Participating Organizations

3M Company

3M Company

Amgen Inc.

Amgen Inc.

Bristol-Myers Squibb

Bristol-Myers Squibb

CSL Behring, LLC

CSL Behring, LLC

Cytiva

Cytiva

EMD Millipore Corporation

EMD Millipore Corporation

Eli Lilly and Company

Eli Lilly and Company

Emerson Automation Solutions

Emerson Automation Solutions

GlaxoSmithKline, LLC

GlaxoSmithKline, LLC

Janssen Research & Development, LLC

Janssen Research & Development, LLC

Merck Sharp & Dohme LLC

Merck Sharp & Dohme LLC

Pfizer, Inc.

Pfizer, Inc.

Sanofi

Sanofi

Sartorius Stedim

Sartorius Stedim