PI – DNP Development & Adoption

Standard software allowing true plug and play of unit op components, reducing automation changes from months to days.

Project status

100% Completed

Industry Need

Automation changes take weeks to months, often on critical path for tech transfer.

Solution

Standard and software allowing true plug and play of unit op components.

Outputs/Deliverables

Interchangeability Demonstrations – SMART O2 sensors from different vendors used to connect to same HMI using the DNP / MTP automation platform while in-process (Complete December 7, 2021).
Reconfigurability Demonstrations – added new processing capability (glucose control) during pre-process equipment setup without re-programming the HMI and process orchestration layer (Complete July 11, 2023) .
Randolph, P., Rode, C., Polilli, B., Fejoz, L., Reinbigler, R., Phillips, M., Hart, R., Erickson, J., Kaneshiro, S. Bringing Flexibility to Integrated Continuous Biomanufacturing. Poster presentation at ICB, October 12, 2022.

Impacts

Reduce reconfiguration downtime from months to days (assume 4 wks savings).

Publications

Additional Project Information (Members Only)

Updates
Value Proposition
Related Publications
Deliverables

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Project Lead

NIIMBL

Participating Organizations

3M Company

Amgen Inc.

Bristol-Myers Squibb

CSL Behring, LLC

Cytiva

Eli Lilly and Company

Emerson Automation Solutions

GlaxoSmithKline, LLC

Janssen Research & Development, LLC

Merck Sharp & Dohme LLC

MilliporeSigma/EMD Serono

Pfizer, Inc.

Sanofi

Sartorius Stedim

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