Interoperable Model Module to Simulate Scale-Dependent Effects during Cell Culture Production of Glycosylated Proteins Request for Application (RFA2025.01)

NIIMBL is pleased to announce this Request for Application (RFA) to participate in the Big Data Program initiative to Simulate Scale-Dependent Effects during Cell Culture Production of Glycosylated Proteins.

Objectives of the project: Develop software modules which are interoperable with others developed for the NIIMBL Big Data Program modeling and simulation team for protein glycosylation prediction. The newly developed modules will incorporate scale-dependent effects common in biopharmaceutical manufacturing and increase accuracy of cell culture process and protein glycosylation profile predictions for all scales. 

Through this RFA, NIIMBL intends to fund one project with funding up to $300,000.

Download RFA2025.1
Access the RFA Submission Hub

Key Dates

May 13, 2025RFA Release
July 7, 2025 RFA Submission Deadline
Mid-July – Mid-August, 2025Submission Review Period
Mid-August, 2025Award Decision Announced
Mid-October, 2025Project Start Date

Templates & Guides

Appendix C: Project Plan 12-months (.docx)
Appendix D: Budget (.xlsx)
Appendix D: Total Project Cost Justification (.docx)
Appendix I: Letter of Intent - FDP Style (.doc)
Appendix I: Subrecipient Commitment Form (.pdf)
Guide for Cost Share (.pdf)
Guide for Federal Stakeholders (.pdf)
Guide for Human Subjects Research (.pdf)
Guide for Vertebrate Animals (.pdf)

Questions

If you have questions regarding this RFA, contact us at [email protected].

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