Optimize Long-read Next Generation Sequencing (NGS)-based Methods Request for Application (RFA2025.1)

NIIMBL is pleased to announce this Request for Application (RFA) to participate in the Viral Vector Program‘s initiative on optimizing long-read NGS capabilities.

Through this RFA, NIIMBL intends to fund a team to determine the capabilities of long-read NGS-based methods to serve as characterization and potentially quality control methods for AAV-based viral vectors. Such capabilities have the potential to improve modality and process understanding; translating to lower risks and greater patient outcomes in AAV vectored gene therapies. 

This study may be used to inform a future inter-laboratory study for this NGS application.