Optimize Long-read Next Generation Sequencing (NGS)-based Methods Request for Application (RFA2025.1)

NIIMBL is pleased to announce this Request for Application (RFA) to participate in the Viral Vector Program‘s initiative on optimizing long-read NGS capabilities.

Through this RFA, NIIMBL intends to fund a team to determine the capabilities of long-read NGS-based methods to serve as characterization and potentially quality control methods for AAV-based viral vectors. Such capabilities have the potential to improve modality and process understanding; translating to lower risks and greater patient outcomes in AAV vectored gene therapies. 

This study may be used to inform a future inter-laboratory study for this NGS application.

Download RFA2025.1
Access the RFA Submission Hub

Key Dates

March 4, 2025RFA Release
April 3, 2025 (5 pm ET)RFA Submission Deadline
April 7 – 30, 2025Submission Review Period
~ May 2, 2025Award Decision Announced
August 1, 2025Project Start Date

Templates & Guides

Appendix C: Project Plan 9-months (.docx)
Appendix D: Budget (.xlsx)
Appendix D: Total Project Cost Justification (.docx)
Appendix I: Letter of Intent - FDP Style (.doc)
Appendix I: Subrecipient Commitment Form (.pdf)
Guide for Federal Stakeholders (.pdf)

Questions

If you have questions regarding this RFA, contact us at [email protected].

Become a member

We offer a variety of membership options that give you the flexibility to choose your organization’s level of engagement based on technology interests and priorities.